Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 24145
Gene Symbol: PANX1
PANX1
CUI: C0085548
Disease: Autosomal Recessive Polycystic Kidney Disease
Autosomal Recessive Polycystic Kidney Disease 		0.200 Biomarker RGD Knockout of 31630543

2019
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.500 Therapeutic RGD Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation. 31462075

2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		0.200 Biomarker RGD The combination of 31409163

2020
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.300 ModifyingMutation RGD Moreover, the clinical relevance to HCC progression of the combined high miR-106b-5p and low FOG2 expression was more significant than high miR-106b-5p alone. 31406464

2019
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.200 ModifyingMutation RGD MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2. 31406464

2019
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.200 ModifyingMutation RGD MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2. 31406464

2019
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.200 ModifyingMutation RGD MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2. 31406464

2019
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
CUI: C2676033
Disease: Hepatoblastoma Caused By Somatic Mutation
Hepatoblastoma Caused By Somatic Mutation 		0.200 ModifyingMutation RGD MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2. 31406464

2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0002103
Disease: Atopic rhinitis
Atopic rhinitis 		0.200 Therapeutic RGD [Acupoint application of herbal paste relieves symptoms and naso-mucosal inflammatory response by down-regulating serum TGF-β1 in allergic rhinitis rats]. 31368266

2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Therapeutic RGD Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats. 31342809

2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Therapeutic RGD Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats. 31342809

2019
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2
CUI: C0028754
Disease: Obesity
Obesity 		0.300 Biomarker RGD To evaluate the effects of probiotic supplementation on chemerin level, inflammation, and metabolic syndrome components in obese Wistar rats. 31284705

2019
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0001306
Disease: Acute alcoholic liver disease
Acute alcoholic liver disease 		0.200 Therapeutic RGD Optimal ratio of 18α- and 18β-glycyrrhizic acid for preventing alcoholic hepatitis in rats. 31258651

2019
Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1
CUI: C0033687
Disease: Proteinuria
Proteinuria 		0.200 Biomarker RGD Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na 31250553

2019
Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		0.200 Therapeutic RGD Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na 31250553

2019
Entrez Id: 84329
Gene Symbol: HVCN1
HVCN1
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		0.200 Biomarker RGD Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na 31250553

2019
Entrez Id: 406957
Gene Symbol: MIR181C
MIR181C
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.220 Biomarker RGD Expression of miR-181c in HCC cells was also significantly lower than it was in normal human liver cells. miR-181c regulated the migration, invasion, apoptosis, and proliferation of HCC cell lines in vitro, and tumor development in vivo. 31114379

2019
Entrez Id: 406957
Gene Symbol: MIR181C
MIR181C
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.200 Biomarker RGD MicroRNA‑181c suppresses growth and metastasis of hepatocellular carcinoma by modulating NCAPG. 31114379

2019
Entrez Id: 406957
Gene Symbol: MIR181C
MIR181C
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.200 Biomarker RGD MicroRNA‑181c suppresses growth and metastasis of hepatocellular carcinoma by modulating NCAPG. 31114379

2019
Entrez Id: 406957
Gene Symbol: MIR181C
MIR181C
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.200 Biomarker RGD MicroRNA‑181c suppresses growth and metastasis of hepatocellular carcinoma by modulating NCAPG. 31114379

2019
Entrez Id: 406957
Gene Symbol: MIR181C
MIR181C
CUI: C2676033
Disease: Hepatoblastoma Caused By Somatic Mutation
Hepatoblastoma Caused By Somatic Mutation 		0.200 Biomarker RGD MicroRNA‑181c suppresses growth and metastasis of hepatocellular carcinoma by modulating NCAPG. 31114379

2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
CUI: C0028754
Disease: Obesity
Obesity 		0.200 Biomarker RGD The expression and activity of phase I enzymes (CYP1A2, CYP2B1, CYP2C11, CYP3A1, CYP4A1 and FMO1) and phase II enzymes (UGT1A1, UGT1A3, UGT1A6, UGT1A9, UGT2B7, NAT1 and GSTT1) were decreased in the liver of obese rats. 31063713

2019
Entrez Id: 128178
Gene Symbol: EDARADD
EDARADD
CUI: C0029882
Disease: Otitis Media
Otitis Media 		0.200 Biomarker RGD Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia. 31028034

2019
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.300 Biomarker RGD Aerobic exercise decreases chemerin/CMKLR1 in the serum and peripheral metabolic organs of obesity and diabetes rats by increasing PPARγ. 30873215

2019
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2
CUI: C0028754
Disease: Obesity
Obesity 		0.300 Biomarker RGD Besides serum chemerin, the levels of chemerin/CMKLR1 in the metabolic organs of obesity and diabetes rats were alleviated by exercise, which were likely to be associated with the improvement of glycolipid metabolism. 30873215

2019